Antigenic Characterization of H3 Subtypes of Avian Influenza A Viruses from North America
Identifieur interne : 000463 ( Main/Exploration ); précédent : 000462; suivant : 000464Antigenic Characterization of H3 Subtypes of Avian Influenza A Viruses from North America
Auteurs : Elizabeth Bailey [États-Unis] ; Li-Ping Long [États-Unis] ; Nan Zhao [États-Unis] ; Jeffrey S. Hall [États-Unis] ; John A. Baroch [États-Unis] ; Jacqueline Nolting [États-Unis] ; Lucy Senter [États-Unis] ; Frederick L. Cunningham [États-Unis] ; G. Todd Pharr [États-Unis] ; Larry Hanson [États-Unis] ; Richard Slemons [États-Unis] ; Thomas J. Deliberto [États-Unis] ; Xiu-Feng Wan [États-Unis]Source :
- Avian diseases [ 0005-2086 ] ; 2016.
Abstract
Besides humans, H3 subtypes of influenza A viruses (IAVs) can infect various animal hosts including avian, swine, equine, canine, and sea mammals. These H3 viruses are both antigenically and genetically diverse. Here we characterized the antigenic diversity of contemporary H3 avian IAVs recovered from migratory birds in North America. Hemagglutination inhibition (HI) assays were performed on 37 H3 isolates of avian IAVs recovered from 2007 to 2011 using generated reference chicken sera. These isolates were recovered from samples taken in the Atlantic, Mississippi, Central, and Pacific waterfowl migration flyways. Antisera to all the tested H3 isolates cross-reacted with each other, and, to a lesser extent, with those to H3 canine and H3 equine IAVs. Antigenic cartography showed that the largest antigenic distance among the 37 avian IAVs is about 4 units, and each unit corresponds to a 2log2 difference in the HI titer. However, none of the tested H3 IAVs cross-reacted with ferret sera derived from contemporary swine and human IAVs. Our results showed that the H3 avian IAVs we tested lacked significant antigenic diversity, and these viruses were antigenically different from those circulating in swine and human populations. This suggests that H3 avian IAVs in North American waterfowl are antigenically relatively stable.
Url:
DOI: 10.1637/11086-041015-RegR
PubMed: 27309078
PubMed Central: 4911812
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000796
- to stream Pmc, to step Curation: 000796
- to stream Pmc, to step Checkpoint: 000340
- to stream Ncbi, to step Merge: 000C89
- to stream Ncbi, to step Curation: 000C89
- to stream Ncbi, to step Checkpoint: 000C89
- to stream Main, to step Merge: 000463
- to stream Main, to step Curation: 000463
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Antigenic Characterization of H3 Subtypes of Avian Influenza A Viruses from North America</title><author><name sortKey="Bailey, Elizabeth" sort="Bailey, Elizabeth" uniqKey="Bailey E" first="Elizabeth" last="Bailey">Elizabeth Bailey</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762</wicri:regionArea><placeName><region type="state">État du Mississippi</region></placeName></affiliation></author><author><name sortKey="Long, Li Ping" sort="Long, Li Ping" uniqKey="Long L" first="Li-Ping" last="Long">Li-Ping Long</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762</wicri:regionArea><placeName><region type="state">État du Mississippi</region></placeName></affiliation></author><author><name sortKey="Zhao, Nan" sort="Zhao, Nan" uniqKey="Zhao N" first="Nan" last="Zhao">Nan Zhao</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762</wicri:regionArea><placeName><region type="state">État du Mississippi</region></placeName></affiliation></author><author><name sortKey="Hall, Jeffrey S" sort="Hall, Jeffrey S" uniqKey="Hall J" first="Jeffrey S." last="Hall">Jeffrey S. Hall</name><affiliation wicri:level="2"><nlm:aff id="A2">USGS National Wildlife Health Center, Madison, Wisconsin, 53711 USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>USGS National Wildlife Health Center, Madison, Wisconsin</wicri:regionArea><placeName><region type="state">Wisconsin</region></placeName></affiliation></author><author><name sortKey="Baroch, John A" sort="Baroch, John A" uniqKey="Baroch J" first="John A." last="Baroch">John A. Baroch</name><affiliation wicri:level="2"><nlm:aff id="A3">National Wildlife Research Center, Wildlife Services, Animal and Plant Health Inspection Service, U.S. Department of Agriculture, Fort Collins, Colorado, 80521 USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Wildlife Research Center, Wildlife Services, Animal and Plant Health Inspection Service, U.S. Department of Agriculture, Fort Collins, Colorado</wicri:regionArea><placeName><region type="state">Colorado</region></placeName></affiliation></author><author><name sortKey="Nolting, Jacqueline" sort="Nolting, Jacqueline" uniqKey="Nolting J" first="Jacqueline" last="Nolting">Jacqueline Nolting</name><affiliation wicri:level="2"><nlm:aff id="A4">Department of Veterinary Preventive Medicine, College of Veterinary Medicine, The Ohio State University, Columbus, OH, 43210 USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Veterinary Preventive Medicine, College of Veterinary Medicine, The Ohio State University, Columbus, OH</wicri:regionArea><placeName><region type="state">Ohio</region></placeName></affiliation></author><author><name sortKey="Senter, Lucy" sort="Senter, Lucy" uniqKey="Senter L" first="Lucy" last="Senter">Lucy Senter</name><affiliation wicri:level="2"><nlm:aff id="A5">Department of Clinical Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Clinical Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762</wicri:regionArea><placeName><region type="state">État du Mississippi</region></placeName></affiliation></author><author><name sortKey="Cunningham, Frederick L" sort="Cunningham, Frederick L" uniqKey="Cunningham F" first="Frederick L." last="Cunningham">Frederick L. Cunningham</name><affiliation wicri:level="2"><nlm:aff id="A6">Mississippi Field Station, National Wildlife Research Center, Wildlife Services, Animal and Plant Health Inspection Service, U.S. Department of Agriculture, Mississippi State, Mississippi, 39762 USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Mississippi Field Station, National Wildlife Research Center, Wildlife Services, Animal and Plant Health Inspection Service, U.S. Department of Agriculture, Mississippi State, Mississippi</wicri:regionArea><placeName><region type="state">État du Mississippi</region></placeName></affiliation></author><author><name sortKey="Pharr, G Todd" sort="Pharr, G Todd" uniqKey="Pharr G" first="G. Todd" last="Pharr">G. Todd Pharr</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762</wicri:regionArea><placeName><region type="state">État du Mississippi</region></placeName></affiliation></author><author><name sortKey="Hanson, Larry" sort="Hanson, Larry" uniqKey="Hanson L" first="Larry" last="Hanson">Larry Hanson</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762</wicri:regionArea><placeName><region type="state">État du Mississippi</region></placeName></affiliation></author><author><name sortKey="Slemons, Richard" sort="Slemons, Richard" uniqKey="Slemons R" first="Richard" last="Slemons">Richard Slemons</name><affiliation wicri:level="2"><nlm:aff id="A4">Department of Veterinary Preventive Medicine, College of Veterinary Medicine, The Ohio State University, Columbus, OH, 43210 USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Veterinary Preventive Medicine, College of Veterinary Medicine, The Ohio State University, Columbus, OH</wicri:regionArea><placeName><region type="state">Ohio</region></placeName></affiliation></author><author><name sortKey="Deliberto, Thomas J" sort="Deliberto, Thomas J" uniqKey="Deliberto T" first="Thomas J." last="Deliberto">Thomas J. Deliberto</name><affiliation wicri:level="2"><nlm:aff id="A3">National Wildlife Research Center, Wildlife Services, Animal and Plant Health Inspection Service, U.S. Department of Agriculture, Fort Collins, Colorado, 80521 USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Wildlife Research Center, Wildlife Services, Animal and Plant Health Inspection Service, U.S. Department of Agriculture, Fort Collins, Colorado</wicri:regionArea><placeName><region type="state">Colorado</region></placeName></affiliation></author><author><name sortKey="Wan, Xiu Feng" sort="Wan, Xiu Feng" uniqKey="Wan X" first="Xiu-Feng" last="Wan">Xiu-Feng Wan</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762</wicri:regionArea><placeName><region type="state">État du Mississippi</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27309078</idno><idno type="pmc">4911812</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911812</idno><idno type="RBID">PMC:4911812</idno><idno type="doi">10.1637/11086-041015-RegR</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">000796</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000796</idno><idno type="wicri:Area/Pmc/Curation">000796</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000796</idno><idno type="wicri:Area/Pmc/Checkpoint">000340</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000340</idno><idno type="wicri:Area/Ncbi/Merge">000C89</idno><idno type="wicri:Area/Ncbi/Curation">000C89</idno><idno type="wicri:Area/Ncbi/Checkpoint">000C89</idno><idno type="wicri:doubleKey">0005-2086:2016:Bailey E:antigenic:characterization:of</idno><idno type="wicri:Area/Main/Merge">000463</idno><idno type="wicri:Area/Main/Curation">000463</idno><idno type="wicri:Area/Main/Exploration">000463</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Antigenic Characterization of H3 Subtypes of Avian Influenza A Viruses from North America</title><author><name sortKey="Bailey, Elizabeth" sort="Bailey, Elizabeth" uniqKey="Bailey E" first="Elizabeth" last="Bailey">Elizabeth Bailey</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762</wicri:regionArea><placeName><region type="state">État du Mississippi</region></placeName></affiliation></author><author><name sortKey="Long, Li Ping" sort="Long, Li Ping" uniqKey="Long L" first="Li-Ping" last="Long">Li-Ping Long</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762</wicri:regionArea><placeName><region type="state">État du Mississippi</region></placeName></affiliation></author><author><name sortKey="Zhao, Nan" sort="Zhao, Nan" uniqKey="Zhao N" first="Nan" last="Zhao">Nan Zhao</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762</wicri:regionArea><placeName><region type="state">État du Mississippi</region></placeName></affiliation></author><author><name sortKey="Hall, Jeffrey S" sort="Hall, Jeffrey S" uniqKey="Hall J" first="Jeffrey S." last="Hall">Jeffrey S. Hall</name><affiliation wicri:level="2"><nlm:aff id="A2">USGS National Wildlife Health Center, Madison, Wisconsin, 53711 USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>USGS National Wildlife Health Center, Madison, Wisconsin</wicri:regionArea><placeName><region type="state">Wisconsin</region></placeName></affiliation></author><author><name sortKey="Baroch, John A" sort="Baroch, John A" uniqKey="Baroch J" first="John A." last="Baroch">John A. Baroch</name><affiliation wicri:level="2"><nlm:aff id="A3">National Wildlife Research Center, Wildlife Services, Animal and Plant Health Inspection Service, U.S. Department of Agriculture, Fort Collins, Colorado, 80521 USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Wildlife Research Center, Wildlife Services, Animal and Plant Health Inspection Service, U.S. Department of Agriculture, Fort Collins, Colorado</wicri:regionArea><placeName><region type="state">Colorado</region></placeName></affiliation></author><author><name sortKey="Nolting, Jacqueline" sort="Nolting, Jacqueline" uniqKey="Nolting J" first="Jacqueline" last="Nolting">Jacqueline Nolting</name><affiliation wicri:level="2"><nlm:aff id="A4">Department of Veterinary Preventive Medicine, College of Veterinary Medicine, The Ohio State University, Columbus, OH, 43210 USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Veterinary Preventive Medicine, College of Veterinary Medicine, The Ohio State University, Columbus, OH</wicri:regionArea><placeName><region type="state">Ohio</region></placeName></affiliation></author><author><name sortKey="Senter, Lucy" sort="Senter, Lucy" uniqKey="Senter L" first="Lucy" last="Senter">Lucy Senter</name><affiliation wicri:level="2"><nlm:aff id="A5">Department of Clinical Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Clinical Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762</wicri:regionArea><placeName><region type="state">État du Mississippi</region></placeName></affiliation></author><author><name sortKey="Cunningham, Frederick L" sort="Cunningham, Frederick L" uniqKey="Cunningham F" first="Frederick L." last="Cunningham">Frederick L. Cunningham</name><affiliation wicri:level="2"><nlm:aff id="A6">Mississippi Field Station, National Wildlife Research Center, Wildlife Services, Animal and Plant Health Inspection Service, U.S. Department of Agriculture, Mississippi State, Mississippi, 39762 USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Mississippi Field Station, National Wildlife Research Center, Wildlife Services, Animal and Plant Health Inspection Service, U.S. Department of Agriculture, Mississippi State, Mississippi</wicri:regionArea><placeName><region type="state">État du Mississippi</region></placeName></affiliation></author><author><name sortKey="Pharr, G Todd" sort="Pharr, G Todd" uniqKey="Pharr G" first="G. Todd" last="Pharr">G. Todd Pharr</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762</wicri:regionArea><placeName><region type="state">État du Mississippi</region></placeName></affiliation></author><author><name sortKey="Hanson, Larry" sort="Hanson, Larry" uniqKey="Hanson L" first="Larry" last="Hanson">Larry Hanson</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762</wicri:regionArea><placeName><region type="state">État du Mississippi</region></placeName></affiliation></author><author><name sortKey="Slemons, Richard" sort="Slemons, Richard" uniqKey="Slemons R" first="Richard" last="Slemons">Richard Slemons</name><affiliation wicri:level="2"><nlm:aff id="A4">Department of Veterinary Preventive Medicine, College of Veterinary Medicine, The Ohio State University, Columbus, OH, 43210 USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Veterinary Preventive Medicine, College of Veterinary Medicine, The Ohio State University, Columbus, OH</wicri:regionArea><placeName><region type="state">Ohio</region></placeName></affiliation></author><author><name sortKey="Deliberto, Thomas J" sort="Deliberto, Thomas J" uniqKey="Deliberto T" first="Thomas J." last="Deliberto">Thomas J. Deliberto</name><affiliation wicri:level="2"><nlm:aff id="A3">National Wildlife Research Center, Wildlife Services, Animal and Plant Health Inspection Service, U.S. Department of Agriculture, Fort Collins, Colorado, 80521 USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Wildlife Research Center, Wildlife Services, Animal and Plant Health Inspection Service, U.S. Department of Agriculture, Fort Collins, Colorado</wicri:regionArea><placeName><region type="state">Colorado</region></placeName></affiliation></author><author><name sortKey="Wan, Xiu Feng" sort="Wan, Xiu Feng" uniqKey="Wan X" first="Xiu-Feng" last="Wan">Xiu-Feng Wan</name><affiliation wicri:level="2"><nlm:aff id="A1">Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762</wicri:regionArea><placeName><region type="state">État du Mississippi</region></placeName></affiliation></author></analytic><series><title level="j">Avian diseases</title><idno type="ISSN">0005-2086</idno><idno type="eISSN">1938-4351</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>SUMMARY</title><p id="P1">Besides humans, H3 subtypes of influenza A viruses (IAVs) can infect various animal hosts including avian, swine, equine, canine, and sea mammals. These H3 viruses are both antigenically and genetically diverse. Here we characterized the antigenic diversity of contemporary H3 avian IAVs recovered from migratory birds in North America. Hemagglutination inhibition (HI) assays were performed on 37 H3 isolates of avian IAVs recovered from 2007 to 2011 using generated reference chicken sera. These isolates were recovered from samples taken in the Atlantic, Mississippi, Central, and Pacific waterfowl migration flyways. Antisera to all the tested H3 isolates cross-reacted with each other, and, to a lesser extent, with those to H3 canine and H3 equine IAVs. Antigenic cartography showed that the largest antigenic distance among the 37 avian IAVs is about 4 units, and each unit corresponds to a 2log2 difference in the HI titer. However, none of the tested H3 IAVs cross-reacted with ferret sera derived from contemporary swine and human IAVs. Our results showed that the H3 avian IAVs we tested lacked significant antigenic diversity, and these viruses were antigenically different from those circulating in swine and human populations. This suggests that H3 avian IAVs in North American waterfowl are antigenically relatively stable.</p></div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Colorado</li><li>Ohio</li><li>Wisconsin</li><li>État du Mississippi</li></region></list><tree><country name="États-Unis"><region name="État du Mississippi"><name sortKey="Bailey, Elizabeth" sort="Bailey, Elizabeth" uniqKey="Bailey E" first="Elizabeth" last="Bailey">Elizabeth Bailey</name></region><name sortKey="Baroch, John A" sort="Baroch, John A" uniqKey="Baroch J" first="John A." last="Baroch">John A. Baroch</name><name sortKey="Cunningham, Frederick L" sort="Cunningham, Frederick L" uniqKey="Cunningham F" first="Frederick L." last="Cunningham">Frederick L. Cunningham</name><name sortKey="Deliberto, Thomas J" sort="Deliberto, Thomas J" uniqKey="Deliberto T" first="Thomas J." last="Deliberto">Thomas J. Deliberto</name><name sortKey="Hall, Jeffrey S" sort="Hall, Jeffrey S" uniqKey="Hall J" first="Jeffrey S." last="Hall">Jeffrey S. Hall</name><name sortKey="Hanson, Larry" sort="Hanson, Larry" uniqKey="Hanson L" first="Larry" last="Hanson">Larry Hanson</name><name sortKey="Long, Li Ping" sort="Long, Li Ping" uniqKey="Long L" first="Li-Ping" last="Long">Li-Ping Long</name><name sortKey="Nolting, Jacqueline" sort="Nolting, Jacqueline" uniqKey="Nolting J" first="Jacqueline" last="Nolting">Jacqueline Nolting</name><name sortKey="Pharr, G Todd" sort="Pharr, G Todd" uniqKey="Pharr G" first="G. Todd" last="Pharr">G. Todd Pharr</name><name sortKey="Senter, Lucy" sort="Senter, Lucy" uniqKey="Senter L" first="Lucy" last="Senter">Lucy Senter</name><name sortKey="Slemons, Richard" sort="Slemons, Richard" uniqKey="Slemons R" first="Richard" last="Slemons">Richard Slemons</name><name sortKey="Wan, Xiu Feng" sort="Wan, Xiu Feng" uniqKey="Wan X" first="Xiu-Feng" last="Wan">Xiu-Feng Wan</name><name sortKey="Zhao, Nan" sort="Zhao, Nan" uniqKey="Zhao N" first="Nan" last="Zhao">Nan Zhao</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/H2N2V1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000463 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000463 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= H2N2V1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:4911812
|texte= Antigenic Characterization of H3 Subtypes of Avian Influenza A Viruses from North America
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:27309078" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a H2N2V1
| This area was generated with Dilib version V0.6.33. |  |